@Cari. I am of the opinion that if something is off one should first assess what they are currently doing in terms of diet, environment, thought processes, and stressors. If nothing happens with those adjustments maybe go to a hair analysis to see if there are any missing nutrients that are not being absorbed at the cellular level.
Where I disagree with Dr Kaufman is on inflammation, yes it is a defence mechanism the body uses to respond to many invaders or harmful stimulants we are exposed to, but to ignore this signal and allow it to become chronic, can lead to other issues more serious in nature down the road later.
As for supplements, I also think that it is prudent to be aware of the fact that a good portion of supplements on the market are manufactured by the same pharmaceutical companies that produce the drugs that we are trying to avoid going on to in order to achieve an endpoint that when looked at closely usually has little to no bearing on longevity but do tend to bring a decline in the quality of life for not only the patient but also those in their circle.
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J.R.K