Reply To: Cancer is a metabolic disease. Dr Thomas Seyfried

[Zack-Vegas]

I don’t know, doesn’t seem like much of a positive step forward to me.  He admits that cancer is a disruption of Oxidative Phosphorylation, and then starts to recommend protocols that will further impair Oxidative Phosphorylation.  His recommendations makes me think he didn’t learn about the basic biology of the processes he’s discussing.

How about, instead of a keto diet, trying to supplement with Krebs cycle intermediates that could help kick start Oxidative Phosphorylation, like succinate?  Or maybe offsetting lactate by supplementing pyruvate?  Or supplementing thyroid? Or, using extra fructose or sucrose to Oxidative Phosphorylation from a different pathway?

Trying to starve the body of glutamine and glucose seems like a recipe for cachexia, which is what a lot of cancer patients actually die from.  Just like a low calcium diet ignores the fact that we have a skeleton, a keto diet low in glucose and glutamine ignores the fact that we have muscle mass and vital organs, which contain a large amount of glutamine, and gluconeogenesis, the process that makes glucose out of almost all the amino acids.  Rather than the near impossible of task of trying to get rid of glutamine and glucose to stop fermentation, why not try to stop bacteria, which are crucial to the fermentation process?  I would think an antibiotic regimen would be much safer.

And again, this seems to be another cancer researcher completely blind to the role of iron.  What is in a lot of “processed carbohydrates?”  Ferrous sulfate, aka, iron, and iron devoid of the protective plant and animal protections that you would get from something like spinach or steak.  The Zacharky studies even demonstrated that lowering iron levels dramatically lowers the risk of both heart disease and cancer.