Reply To: Cancer again – Is this the End, or just the beginning?

[Kevin007]

I think my calculations for MB dosage may be incorrect – I created an HED calculator and came up with the following:

The HED for 50MG/KG per day of MB for a mouse would be as follows:
195lbs = 195/2.2 = 88.6kg
The BSA (body surface area) calculator  gives us a BSA of 2.12m2
This results in a human K*m* factor of 89/2.12 or 42
The K*m* factor for a mouse is 3
The mg/kg HED is (50 x 3) / 41.88 = 3.58
Therefore the complete HED is 3.46mg/kg x 88.6 = 317mg

So somewhere around 300mg over the course of a day.