One of the things that Ray Peat mentioned was that in many studies, they would find ways to make fructose appear harmful, or hide it’s beneficial effects. The study below is a great example. Brad Marshall used this study to discuss the SCD1 enzyme, and how Sterculia Oil can inhibit it (side note- Vitamin E has also been shown to inhibit this very same enzyme). I’ll post the study and abstract in this message, and point out a massive confounder in the next message.
https://www.liebertpub.com/doi/abs/10.1089/jmf.2019.0177
Abstract- The metabolic syndrome (MS) underlies metabolic disorders considered risk factors for the development of diabetes and cardiovascular diseases, which are major causes of morbidity and mortality in most of the world. Sterculic acid has been proposed as a potential tool for the treatment of MS since it inhibits the activity of the stearoyl-CoA desaturase-1 (SCD1), a central enzyme in lipid metabolism. We analyzed the effect of sterculic oil (SO) co-administration with 30% fructose in drinking water on the development of MS in male Wistar rats. After 8 weeks, 0.4% SO exerted a protective effect from MS development since parameters altered by fructose (blood pressure, insulin resistance, serum glucose and triglycerides, steatosis, and adiposity) were similar to those of control rats.
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