“Also about endotoxin apparently saturated fat or fats in general can cause endotoxemia? so more points for low fat?
https://diabetesjournals.org/care/article/41/8/1732/36380/Saturated-Fat-Is-More-Metabolically-Harmful-for @Zack vegas”
If you are going to look at studies, you need to actually read them to see if they are relevant, or valid to the point you are trying to make. Science is never done in a vacuum, and there has been a campaign to demonize Saturated Fat and promote high PUFA oils going on since the 1970s. This study was done during that time, and published by an organization that promotes this view. So already, you need to be on guard.
The section that describes the diets shows why this study can’t be used to support the idea that Saturated Fat increases endotoxin-
“The overfeeding diets were provided to participants and consisted in the SAT group of 30 g coconut oil, 40 g butter, **and 100 g 40% fat containing blue cheese** as extra energy per day; in the UNSAT group of 36 g olive oil, 26 g pesto, 54 g pecan nuts, and 20 g butter; and in the CARB group of 2.8 dL orange juice, 4.3 dL sugar-sweetened beverage, and 200 g candy.”
Blue cheese is moldy cheese, by definition. 100g is roughly 3.5 ounces, which is a pretty big serving size. This is a massive confounder, as the other two groups did not feature any additional fermented foods, or foods deliberately loaded up with mold during processing. Why didn’t they use a rennet based and more commonly eaten cheese like cheddar? Unless the goal was to rig the study, and then draw absurd conclusions?
This study does not support the idea that saturated fat itself increases endotoxin. It supports the idea that saturated fat plus a fermented food loaded with mold (and likely a lot of endotoxin itself) will increase endotoxin.
Author
