If the charge is positive in context of the lipid nanoparticle in the COVID-19 gene therapies if there is a positive charge I believe that it will go to the lungs, if it is a negative charge in excess this will lead to clot formation, think in terms of the long fibrin clots that the embalmers are reporting. There is a very small window of tolerance for these two possibilities to not occur. Neither are ideal and is one of the reasons that this platform requires twenty four seven observation by medical staff when administered for its original purpose in cancer treatment experimentation.
Author
J.R.K